GLP-1 Bitter Complex

GLP-1 Bitter Complex by MediHerb is a satiety-regulating hops extract and feverfew supplement to support the healthy secretion of GLP-1, CCK and PYY hormones.*

The herbs in GLP-1 Bitter Complex are traditionally used in Western herbal preparations and in a growing body of preliminary research to help:

• Support healthy secretion of satiety-regulating hormones: glucagon-like peptide-1 (GLP-1), cholecystokinin (CCK), and peptide YY (PYY)*
• Stimulate bitter taste gastric secretions*
• Promote healthy digestion and gastrointestinal function*

Healthy lifestyle habits. GLP-1 Bitter Complex is designed to complement a healthy diet and lifestyle. We encourage patients to include protein with meals, choose fiber-rich whole foods, stay well hydrated, prioritize 7–9 hours of sleep, and engage in regular physical activity.

Recommend a gradual dose build-up. Patients should begin with 1 softgel daily, 30–60 minutes before their main meal. If the initial dose is well tolerated, they can increase to 2 softgels daily in Week 2, then 3 softgels daily from Week 3 onward, taking 1 before each main meal. Dose increases should occur every 3–7 days, progressing only when the current dose is comfortable and consistent with your guidance.

Some patients may experience digestive discomfort when starting, including occasional nausea, stomach discomfort, or loose stools. If symptoms occur, we advise you to not to increase your dose. Remain at or return to the last comfortable dose, try taking the softgels with food during dose build-up, and resume increases more gradually once symptoms settle. We encourage patients to contact us if symptoms are severe, concerning, or persistent.